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Weil's disease (/ ˈ v aɪ l z / VILES), [12] the acute, severe form of leptospirosis, causes the infected individual to become jaundiced (skin and eyes become yellow), develop kidney failure, and bleed. [6] Bleeding from the lungs associated with leptospirosis is known as severe pulmonary haemorrhage syndrome. [5]
Leptospirosis is treated with the antibiotics doxycycline and penicillin. [28] There are more than 200 diverse pathogenic Leptospira serovars, making it challenging to develop an effective vaccine. [31] However, vaccines for the serovars known as Hardjo, Pomona, Canicola, Grippotyphosa and icterohaemorrhagiae have been developed.
L. interrogans can also obtain iron from heme, which is bound to most of the iron in the human body. The HbpA hemin-binding protein, which may be involved in the uptake of hemin , has been identified on the surface of L. interrogans [ 35 ] Although other pathogenic species of Leptospira and L. biflexa lack HbpA, yet another hemin-binding ...
Flu vaccines used during the flu in 2009. This is a list of vaccine-related topics.. A vaccine is a biological preparation that improves immunity to a particular disease.A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins.
The disease was first reported in the town of O'Higgins in Buenos Aires province, Argentina in 1958, giving it one of the names by which it is known. [2] Theories about its nature included: Weil's disease, leptospirosis, chemical pollution. [2] It was associated with fields containing stubble after the harvest, giving it another of its names.
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has
Vaccine-preventable deaths are usually caused by a failure to obtain the vaccine in a timely manner. This may be due to financial constraints or to lack of access to the vaccine. A vaccine that is generally recommended may be medically inappropriate for a small number of people due to severe allergies or a damaged immune system. In addition, a ...