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When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. [10] [11] Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality risk in tobacco smokers ...
Other pneumatoses in the lungs are focal (localized) blebs and bullae, pulmonary cysts and cavities. Pneumoperitoneum (or peritoneal emphysema) is air or gas in the abdominal cavity, and is most commonly caused by gastrointestinal perforation, often the result of surgery. Pneumarthrosis, the presence of air in a joint, is rarely a serious sign.
Diffuse alveolar damage (DAD) is a histologic term used to describe specific changes that occur to the structure of the lungs during injury or disease. Most often DAD is described in association with the early stages of acute respiratory distress syndrome ( ARDS ). [ 1 ]
Interstitial lung disease (ILD), or diffuse parenchymal lung disease (DPLD), [3] is a group of respiratory diseases affecting the interstitium (the tissue) and space around the alveoli (air sacs) of the lungs. [4] It concerns alveolar epithelium, pulmonary capillary endothelium, basement membrane, and perivascular and perilymphatic tissues. It ...
Restrictive lung diseases are a category of extrapulmonary, pleural, or parenchymal respiratory diseases that restrict lung expansion, [2] resulting in a decreased lung volume, an increased work of breathing, and inadequate ventilation and/or oxygenation. Pulmonary function test demonstrates a decrease in the forced vital capacity.
In the UK, approximately 1 in 7 individuals are affected by some form of chronic lung disease, most commonly chronic obstructive pulmonary disease, which includes asthma, chronic bronchitis and emphysema. [32] Respiratory diseases (including lung cancer) are responsible for over 10% of hospitalizations and over 16% of deaths in Canada. [33]
Therapy interventions for respiratory compromise target secondary effects of the condition, which manifest as pulmonary pathologies or aggravate existing pulmonary conditions. Appropriately administered antibiotic therapy can reduce the risk of mortality in patients with moderate to severe pneumonia , and timely ventilation therapy can reduce ...
Decrease of total lung area, e.g. Restrictive lung disease or lung resection (partial or total). Chronic obstructive pulmonary disease (Emphysema) due to decreased surface area in the alveoli, as well as damage to the capillary bed [7] Pulmonary embolism; Cardiac insufficiency [8] Pulmonary hypertension; Bleomycin (upon administration of more ...
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