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Cat with chronic kidney disease and typical symptoms: fatigue, emaciation and dull, shaggy coat. The chronic kidney disease of the cat (CNE) - also called chronic renal insufficiency (CNI) or chronic renal failure in the older literature - is an incurable, progressive disease characterized by a gradual decrease in the nephrons and thus to a decreasing function (insufficiency) of the kidneys.
Feline cystitis means "inflammation of the bladder in cats". The term idiopathic means unknown cause; however, certain behaviours have been known to aggravate the illness once it has been initiated. It can affect both males and females of any breed of cat. It is more commonly found in female cats; however, when males do exhibit cystitis, it is ...
The disease begins when the cat stops eating from a loss of appetite, forcing the liver to convert body fat into usable energy. Feline lower urinary tract disease is a term that is used to cover many problems of the feline urinary tract, including stones and cystitis. The term feline urologic syndrome is an older term which is still sometimes ...
In 10-20% of cats increased serum concentration of blood urea nitrogen is observed. Although the prevalence of hyperthyroid cats with chronic kidney disease is higher than this due to how hyperthyroidism results in an increase to the glomerular filtration rate. Most cats with chronic kidney disease and hyperthyroidism have the kidney disease go ...
Feline idiopathic cystitis (FIC) is by far the most common form of FLUTD in young to middle-aged cats. It is a disease whose cause is not fully understood but is thought to be related to stress events and a cat's pre-disposition to anxiety, as well as certain lifestyle choices (e.g. a dry food diet, no access to outdoor space).
Ornithine transcarbamylase, the defective enzyme in this disorder, is the final enzyme in the proximal portion of the urea cycle, responsible for converting carbamoyl phosphate and ornithine into citrulline. OTC deficiency is inherited in an X-linked recessive manner, meaning males are more commonly affected than females.
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