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Insulin resistance, or low insulin sensitivity, happens when cells throughout the body don’t respond properly to the hormone insulin, especially cells in muscles, fat and the liver. Insulin is a ...
Other prevailing thoughts that insulin resistance can be an evolutionary adaptation include the thrifty gene hypothesis. This hypothesis raises the point that if there is a genetic component to insulin resistance and Type 2 diabetes, these phenotypes should be selected against. [74]
IR is insulin resistance and %β is the β-cell function (more precisely, an index for glucose tolerance, i.e. a measure for the ability to counteract the glucose load). Insulin is given in μU/mL. [7] Glucose and insulin are both during fasting. [2] This model correlated well with estimates using the euglycemic clamp method (r = 0.88). [2]
Type 2 diabetes is characterized by insulin resistance, which may be combined with relatively reduced insulin secretion. [12] The defective responsiveness of body tissues to insulin is believed to involve the insulin receptor. [59] However, the specific defects are not known. Diabetes mellitus cases due to a known defect are classified separately.
A 2021 study in Nutrients found that a high-protein diet was more effective than the Mediterranean diet at reducing insulin resistance and improving glycemic variability—a risk factor for type 2 ...
Insulin Resistance and Diabetes, Centers for Disease Control and Prevention. A plant-based diet for the prevention and treatment of type 2 diabetes, Journal of Geriatric Cardiology.
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