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Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
AH-1058 is a lipophilic antiarrhythmic calcium channel blocker synthesized by the Pharmaceutical Research Laboratories of Ajinomoto Co., Inc in Kawasaki, Japan. [1] It is derived from cyproheptadine, a compound with known antiserotonic, antihistaminic and calcium channel blocking properties.
Here are links to possibly useful sources of information about Cyproheptadine. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
Cyproheptadine blocks 5-HT 2A, H1 and is a mild anticholinergic. Methysergide is a 5-HT 2A antagonist and nonselective 5-HT 1 receptor blocker. It causes retroperitoneal fibrosis and mediastinal fibrosis. [citation needed] Quetiapine blocks 5-HT 2A, 5-HT 1A, dopamine receptors D 1 and D 2, histamine receptor H1, and A1 adrenoreceptors.
Apetamin is a potentially dangerous figure-augmentation product. [1] [2] It is a syrup containing cyproheptadine, the amino acid lysine, and some vitamins.Cyproheptadine, the active ingredient, is an antihistamine and a hepatotoxin that has many effects on the body, including increased appetite, fatigue, and drowsiness. [3]
The following other wikis use this file: Usage on ar.wikipedia.org سيبروهيبتادين; Usage on azb.wikipedia.org سیپروهپتادین
All three of these agents, pizotifen, cyproheptadine, and clozapine act as non-selective monoamine receptor antagonists. [10] Pizotifen also fully blocks the effects of serotonergic psychedelics , including LSD , mescaline , 5-MeO-DMT , and DOM , in drug discrimination tests.