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Grape seed extract is sold as a dietary supplement. [6] The US National Center for Complementary and Integrative Health reported that oral administration of grape seed extract (dose and frequency unreported) was well tolerated in people over 14 weeks. [1] Side effects may include itchy scalp, dizziness, headache, and nausea. [1]
[10] [11] A systematic review of trials in 2021 found that the claimed benefits of the protocol could not be confirmed. [12] People in sepsis may have micronutrient deficiencies, including low levels of vitamin C. [13] Reviews mention that an intake of 3.0 g/day via intravenous administration may needed to maintain normal plasma concentrations.
Grapes – fruit, popularized for supposed anti-cancer effect by Johanna Brandt (1876–1964) who championed a "grape diet", and promoted more recently in the form of grape seed extract (GSE). According to the American Cancer Society, "there is very little reliable scientific evidence available at this time that drinking red wine, eating grapes ...
A newer systematic review published in 2010 by Ernst concluded: [7] All placebo-controlled trials failed to demonstrate efficacy. It is concluded that the most reliable clinical trials do not show any differences between flower remedies and placebos.
Grape therapy or grape diet, also known as ampelotherapy, is a diet that involves heavy consumption of grapes, including seeds, and parts of the vine, including leaves, that is a form of alternative medicine. The concept was developed in 19th-century Germany in spas such as Bad Duerkheim and Merano. [1]
Megavitamin therapy is the use of large doses of vitamins, often many times greater than the recommended dietary allowance (RDA) in the attempt to prevent or treat diseases.
Grapefruit seed extract (GSE), also known as citrus seed extract, is a liquid extract derived from the seeds, pulp, and white membranes of grapefruit. [1] GSE is prepared by grinding the grapefruit seed and juiceless pulp, then mixing with glycerin . [ 1 ]
L-α-Glycerophosphorylcholine (alpha-GPC, choline alfoscerate, sn-glycero-3-phosphocholine) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor [1] which has been investigated for its potential for the treatment of Alzheimer's disease [2] and other dementias.
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