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Formulation studies then consider such factors as particle size, polymorphism, pH, and solubility, as all of these can influence bioavailability and hence the activity of a drug. The drug must be combined with inactive ingredients by a method that ensures that the quantity of drug present is consistent in each dosage unit e.g. each tablet.
A research design typically outlines the theories and models underlying a project; the research question(s) of a project; a strategy for gathering data and information; and a strategy for producing answers from the data. [1] A strong research design yields valid answers to research questions while weak designs yield unreliable, imprecise or ...
Hit to lead (H2L) also known as lead generation is a stage in early drug discovery where small molecule hits from a high throughput screen (HTS) are evaluated and undergo limited optimization to identify promising lead compounds.
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]
Physical pharmacy is the branch of pharmacy that concentrates on the applications of physics and chemistry to the study of pharmacy. In other words, it is the study of the effects that dosage forms have on their environment by addressing issues at the molecular level. [1]
Clinical study design is the formulation of trials and experiments, as well as observational studies in medical, clinical and other types of research (e.g., epidemiological) involving human beings. [1]
Sugar-sweetened beverages may increase your risk for heart disease and type 2 diabetes, new research finds. Sugary drinks were found to be linked to over 330,000 deaths a year. Experts explain the ...
The research-based design process is a research process proposed by Teemu Leinonen, [1] [2] inspired by several design theories. [ 3 ] [ 4 ] [ 5 ] It is strongly oriented towards the building of prototypes and it emphasizes creative solutions, exploration of various ideas and design concepts, continuous testing and redesign of the design solutions.