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Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI). [12] The precise mechanism for its antidepressant and anxiolytic effects is not known. [10] Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. [10]
Currently, Duloxetine, an SNRI, is the only FDA-approved medication for pediatric GAD, despite the fact that SSRIs are typically first-line treatment. [ 95 ] [ 96 ] It is suggested that these medications be combined with psychotherapy to maximize effectiveness.
Duloxetine is a serotonin and norepinephrine reuptake inhibitor (SNRI). It is taken orally, most commonly as an antidepressant, often in an extended-release tablet form.
However, in most cases, SSRIs are just as effective as SNRIs. Some of the most common SNRIs are: Duloxetine (Cymbalta) Venlafaxine (Effexor) Levomilnacipran (Fetzima) Desvenlafaxine (Pristiq and ...
Serotonin–norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine (Effexor), its active metabolite desvenlafaxine (Pristiq), and duloxetine (Cymbalta) prevent the reuptake of both serotonin and norepinephrine, however their efficacy appears to be only marginally greater than the SSRIs.
SNRIs. The most commonly prescribed SNRIs are: Venlafaxine (Effexor XR) Desvenlafaxine (Pristiq) Duloxetine (Cymbalta). Milnacipran (Savella) Levomilnacipran (Fetzima)
For example, cocaine, which non-selectively inhibits the reuptake of serotonin, norepinephrine, and dopamine, is an SRI but not an SSRI. SRIs are used predominantly as antidepressants (e.g., SSRIs, SNRIs, and TCAs), though they are also commonly used in the treatment of other psychological conditions such as anxiety disorders and eating disorders.
Duloxetine. Sold under the brand name Cymbalta, duloxetine is an SNRI that’s used to treat generalized anxiety disorder. ... medications like tricyclic antidepressants typically have a higher ...