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The game has been endorsed by the Journal of Cell Science. [1]Alex Rosenwald, in a review for Board Game Quest, stated that the concept of protein synthesis "shines through in all facets of gameplay", with the game mechanics and organelle cell functions aligning into an "immersive experience of creating and transporting various chemicals in and out of the cells". [3]
In a paper and pencil game, players write their own words, often under specific constraints. For example, a crossword requires players to use clues to fill out a grid, with words intersecting at specific letters. Other examples of paper and pencil games include hangman, categories, Boggle, and word searches.
A version of Shiritori using only English words was invented to help people learn English. Most rules are the same, yet there are several original and optional rules that are used. For students of English, any words - including nouns, verbs, and adjectives - can be used.
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The game overall is a mix of Boggle and crossword puzzles. [3] To solve the puzzle, the player must find every word using the letters that are located in the circle at the bottom of the screen. [4] There are anywhere from 3 to 7 letters in the circle, depending on the level being played.
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Some memory B cells can be activated without T cell help, such as certain virus-specific memory B cells, but others need T cell help. [26] Upon antigen binding, the memory B cell takes up the antigen through receptor-mediated endocytosis, degrades it, and presents it to T cells as peptide pieces in complex with MHC-II molecules on the cell ...