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SSRIs, including citalopram, can increase the risk of bleeding, especially when coupled with aspirin, NSAIDs, warfarin, or other anticoagulants. [37] Taking citalopram with omeprazole may cause higher blood levels of citalopram. This is a potentially dangerous interaction, so dosage adjustments may be needed or alternatives may be prescribed.
These opioids (and to a lesser extent oxycodone, tramadol, and methadone) have interaction potential with selective serotonin reuptake inhibitors. [171] [172] The concomitant use of some SSRIs (paroxetine and fluoxetine) with codeine may decrease the plasma concentration of active metabolite morphine, which may result in reduced analgesic efficacy.
Additionally, some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to their primary mechanism of action(s) and this contributes to their side effect and drug interaction profiles. A closely related type of drug is a serotonin releasing agent (SRA), an example of which is ...
Lexapro and alcohol don’t go well together. You may be more likely to develop side effects or drug interactions, or sustain injuries due to changes in your level of motor control.
This includes citalopram, sertraline, fluoxetine, paroxetine and escitalopram. If you’re experiencing ED or other intimate side effects of antidepressants, talk to your healthcare provider.
Two or more antidepressants taken together, from either the same or different classes (affecting the same area of the brain, often at a much higher level). An antipsychotic combined with an antidepressant, particularly atypical antipsychotics such as aripiprazole (Abilify), quetiapine (Seroquel), olanzapine (Zyprexa), and risperidone (Risperdal).
Zoloft is often prescribed off-label to treat PE, because it can make climaxing take longer. ... Lexapro (escitalopram), Celexa (citalopram) and Prozac (fluoxetine). Using bupropion (Wellbutrin).
Amitriptyline is probably effective for the prevention of periodic migraine in adults. Amitriptyline is similar in efficacy to venlafaxine and topiramate but carries a higher burden of adverse effects than topiramate. [16] For many patients, even very small doses of amitriptyline are helpful, which may allow for minimization of side effects. [38]