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  2. Raynaud syndrome - Wikipedia

    en.wikipedia.org/wiki/Raynaud_syndrome

    Patients with secondary Raynaud's can also have symptoms related to their underlying diseases. Raynaud's phenomenon is the initial symptom that presents for 70% of patients with scleroderma, a skin and joint disease. [citation needed] When Raynaud's phenomenon is limited to one hand or one foot, it is referred to as unilateral Raynaud's.

  3. Rare disorder can turn fingers and toes white or blue when it ...

    www.aol.com/lifestyle/rare-disorder-turn-fingers...

    This is the type Smith was diagnosed with after spotting the symptoms in 8th grade. Secondary Raynaud’s — also known as Raynaud's phenomenon — happens because of an underlying disease or ...

  4. Gangrene - Wikipedia

    en.wikipedia.org/wiki/Gangrene

    An illustration showing four different stages of gangrene, including one (Fig. 4 top right) caused by an obstacle to the return of the venous blood due to heart disease. Symptoms may include a change in skin color to red or black, numbness, pain, skin breakdown, and coolness. [1] The feet and hands are most commonly involved. [1]

  5. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    Raynaud's phenomenon is frequently the first manifestation of CREST/lcSSc, preceding other symptoms by years. Stress and cold temperature induce an exaggerated vasoconstriction of the small arteries, arterioles, and thermoregulatory vessels of the skin of the digits. Clinically this manifests as a white-blue-red transition in skin color.

  6. Largest ever genetic study of Raynaud's phenomenon ... - AOL

    www.aol.com/news/study-pinpoints-genes-behind...

    Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...

  7. Acrocyanosis - Wikipedia

    en.wikipedia.org/wiki/Acrocyanosis

    Unless acrocyanosis results from another condition (e.g. malignancy, antiphospholipid syndrome, atherosclerosis, acute ischemic limb, bacterial endocarditis), there is no associated increased risk of disease or death, and there are no known complications. Aside from the discoloration, there are no other symptoms: no pain, and no loss of function.

  8. Erythromelalgia - Wikipedia

    en.wikipedia.org/wiki/Erythromelalgia

    The coexistence of erythromelalgia and Raynaud's phenomenon is rare, but case studies of patients with both diagnoses have been reported in medical journals. [17] Symptoms may present gradually and incrementally, sometimes taking years to become intense enough for patients to seek medical care. In other cases symptoms emerge full blown with onset.

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