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Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
Larix laricina, commonly known as the tamarack, [3] hackmatack, [3] eastern larch, [3] black larch, [3] red larch, [3] or American larch, [3] is a species of larch native to Canada, from eastern Yukon and Inuvik, Northwest Territories east to Newfoundland, and also south into the upper northeastern United States from Minnesota to Cranesville Swamp, West Virginia; there is also an isolated ...
[17] [18] The medication appears to work equally well regardless of sex, [19] although some sex-related differences in treatment response were described. [ 20 ] If there is an underlying history of cardiovascular disease, it has a significant impact on the effects of statin.
The hybrid Dunkeld larch is widely grown as a timber crop in Northern Europe, valued for its fast growth and disease resistance. Larch on oak was the traditional construction method for Scottish fishing boats in the 19th century. [citation needed] Larch has also been used in herbal medicine; see Bach flower remedies and Arabinogalactan for details.
It can be found in conifers like the Siberian larch, Larix sibirica, in Russia, in Pinus roxburghii, [5] in Cedrus deodara [5] and in the Chinese yew, Taxus chinensis var. mairei. [6] It is also found in the silymarin extract from the milk thistle seeds. Taxifolin is present in vinegars aged in cherry wood. [7]
The specificity and the tight binding of statins is due to orientation and bonding interactions that form between the statin and the HMGR enzyme. [9] Polar interactions are formed between the HMG-moiety and residues that are located in the cis loop of the enzyme. These polar interactions are between Ser 684, Asp 690, Lys 691 and Lys 692 (Figure 4
Clinical studies investigating the relationship between flavonoid consumption and cancer prevention or development are conflicting for most types of cancer, probably because most human studies have weak designs, such as a small sample size. [1] [30] There is little evidence to indicate that dietary flavonoids affect human cancer risk in general ...
Larix sibirica, the Siberian larch or Russian larch, is a frost-hardy tree native to western Russia, from close to the Finnish border east to the Yenisei valley in central Siberia, where it hybridises with the Dahurian larch L. gmelinii of eastern Siberia; the hybrid is known as Larix × czekanowskii.