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LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells.
[63] [64] Lichen sclerosus is associated with from 3 to 7% of all cases of vulvar squamous cell carcinoma. [65] In women, it has been reported that 33.6 times higher vulvar cancer risk is associated with LS. [66] [67] A study in men noted that: "the reported incidence of penile carcinoma in patients with balanitis xerotica obliterans is 2.6–5 ...
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
Nearly one in five new cervical cancers diagnosed from 2009 to 2018 were in women 65 and older, according to a new UC Davis study.But what has experts concerned is that, according to the study ...
A 2007 survey of American women found 40% had heard of HPV infection and less than half of those knew it causes cervical cancer. [175] Over a longitudinal study from 1975 to 2000, it was found that people of lower socioeconomic census brackets had higher rates of late-stage cancer diagnosis and higher morbidity rates.
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
An ascus (from Ancient Greek ἀσκός (askós) 'skin bag, wineskin'; pl.: asci) [1] is the sexual spore-bearing cell produced in ascomycete fungi. Each ascus usually contains eight ascospores (or octad), produced by meiosis followed, in most species, by a mitotic cell division.
In the female, these are the ovaries, fallopian tubes, uterus, cervix, vagina and vulva. The primary sex organs are different from the secondary sex organs because at maturity they produce gametes, which are haploid male or female germ cells which can unite with another of the opposite sex during sexual reproduction to form a zygote.