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Phenylboronic acid or benzeneboronic acid, abbreviated as PhB(OH) 2 where Ph is the phenyl group C 6 H 5 - and B(OH) 2 is a boronic acid containing a phenyl substituent and two hydroxyl groups attached to boron. Phenylboronic acid is a white powder and is commonly used in organic synthesis.
4-Formylphenyl boronic acid crystallizes in colorless needles [2] or is obtained as an odorless, whitish powder, which dissolves little in cold but better in hot water. The compound is quite stable [4] and readily forms dimers and cyclic trimeric anhydrides, which complicate purification and tend to protodeboronize, a secondary reaction that occurs frequently in the Suzuki coupling, with ...
Aminomethylbenzoic acid (more precisely, 4-aminomethylbenzoic acid or p-aminomethylbenzoic acid, PAMBA) is an antifibrinolytic. [1] See also. 4-Aminobenzoic acid;
4-Nonylphenylboronic acid is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC 50 of 9.1nM, and 870x selectivity for FAAH over the related enzyme MAGL, which it inhibits with an IC 50 of 7900nM. [1]
1-Boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) is a compound used as an intermediate in the manufacture of fentanyl, as well as various related derivatives such as butyrylfentanyl, furanylfentanyl, benzylfentanyl and homofentanyl, among others.
Phenoxyacetic acid is a white or clear crystalline compound at room temperature. [2] When impure, it can appear to be a light tan to brown. The compound has a solubility in water of 12 g/L and is highly soluble in organic solvents including ethanol, diethyl ether and benzene. Phenoxyacetic acid is a weak acid and weak base with a pKa of 3.7. [1 ...
4-(4-Methylphenyl)-4-oxobutanoic acid is an organic carboxylic acid. The preparation of it is used for undergraduate teaching of organic chemistry synthesis. The preparation of it is used for undergraduate teaching of organic chemistry synthesis.
The first synthesis of 1,3-diphenylisobenzofuran was reported in 1905 by A. Guyot and J. Catel. [9] [10] Phenylmagnesium bromide was reacted with 3-phenylphthalide (the latter accessible from the methyl ester of 3-hydroxyphthalide with phenylboronic acid in 95% yield [11]) to a lactol, which gives with mineral acids upon elimination of water 1,3-diphenylisobenzofuran with 87% yield.