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A lung biopsy is an interventional procedure performed to diagnose lung pathology by obtaining a small piece of lung which is examined under a microscope. [1] [2] Beyond microscopic examination for cellular morphology and architecture, special stains and cultures can be performed on the tissue obtained. [3]
An incisional biopsy or core biopsy samples a portion of the abnormal tissue without attempting to remove the entire lesion or tumor. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration ...
High magnification photomicrograph of a lung biopsy taken showing chronic hypersensitivity pneumonitis , showing mild thickening of the walls of the small air sacs by invasion of white blood cells. A multinucleated giant cell , seen within the walls of the air sacs to the right of the picture halfway down, is an important clue to the correct ...
The diagnosis of lung cancer is based on chest radiograph and computed tomography (CT) scans, and is confirmed by biopsy. Biopsy is usually performed via bronchoscopy or CT-guided biopsy. Treatment and prognosis depend upon the histological type of cancer, the stage, and the patient's performance status. Treatments include surgery, chemotherapy ...
Appearance of usual interstitial pneumonia (UIP) in a surgical lung biopsy at low magnification. The tissue is stained with hematoxylin (purple dye) and eosin (pink dye) to make it visible. The pink areas in this picture represent lung fibrosis (collagen stains pink). Note the "patchwork" (quilt-like) pattern of the fibrosis.
Diagnosis is made via a multi-disciplinary team review of patient history, imaging, lung function testing, and in some cases a surgical lung biopsy. While a lung biopsy is the gold standard, some clinicians opt against this due to the risks of the procedure. Lung biopsies performed on patients with NSIP reveal two different disease patterns ...
Diffuse alveolar damage (DAD): an acute lung condition with the presence of hyaline membranes. [2] These hyaline membranes are made up of dead cells, surfactant , and proteins. [ 1 ] The hyaline membranes deposit along the walls of the alveoli, where gas exchange typically occurs, thereby making gas exchange difficult.
Lung biopsy showing infiltration of lymphatic tissue. Lymphangiomatosis is a condition where a lymphangioma is not present in a single localised mass, but in a widespread or multifocal manner. It is a rare type of tumor which results from an abnormal development of the lymphatic system .