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They are never "hyperchromic". If more than the normal amount of hemoglobin is made, the cells get larger—they do not become darker. [2] It is calculated by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood. MCH=(Hb*10)/RBC (in millions) [3] A normal MCH value in humans is 27 to 33 picograms (pg)/cell ...