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Contrast-enhanced ultrasound (CEUS) is the application of ultrasound contrast medium to traditional medical sonography. Ultrasound contrast agents rely on the different ways in which sound waves are reflected from interfaces between substances. This may be the surface of a small air bubble or a more complex structure.
A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluids within the body in medical imaging. [1] Contrast agents absorb or alter external electromagnetism or ultrasound , which is different from radiopharmaceuticals , which emit radiation themselves.
The most common example of molecular imaging used clinically today is to inject a contrast agent (e.g., a microbubble, metal ion, or radioactive isotope) into a patient's bloodstream and to use an imaging modality (e.g., ultrasound, MRI, CT, PET) to track its movement in the body.
A contrast medium for medical ultrasonography is a formulation of encapsulated gaseous microbubbles [64] to increase echogenicity of blood, discovered by Dr. Raymond Gramiak in 1968 [65] and named contrast-enhanced ultrasound. This contrast medical imaging modality is used throughout the world, [66] for echocardiography in particular in the ...
Iodinated contrast contains iodine.It is the main type of radiocontrast used for intravenous administration.Iodine has a particular advantage as a contrast agent for radiography because its innermost electron ("k-shell") binding energy is 33.2 keV, similar to the average energy of x-rays used in diagnostic radiography.
Lantheus Medical Imaging, GE Healthcare: Ultrasound Contrast Agents: Approved in the US and Europe [8] [28] [9] [29] C 4 F 10-1.9: Bubble: Perfluorobutane: Sonazoid: Daiichi Sankyo: Ultrasound Contrast Agent: Approved in Japan, [10] available in Korea, Norway, Taiwan, and China [30] C 5 F 12: 29: Bubble and/or Droplet: Dodecafluoropentane ...
Contrast agents with therapeutic properties have been under development for several years. [8] One example is the design of contrast agents capable of releasing a chemotherapeutic agent locally at the target site, triggered by a stimulus provided by the operator. This localized approach aims to increase treatment efficacy and minimize side effects.
The Molecular Imaging and Contrast Agent Database or MICAD is a freely accessible online source of information on in vivo molecular imaging agents. It was established as a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, a set of major inter-agency initiatives accelerating medical research and the development of new, more specific therapies for a wide range of ...