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This finding is most commonly associated with hematogenous metastases, where malignant cells spread to the lungs via the bloodstream, forming discrete nodules that resemble cannonballs. [2] The term "cannonball" reflects the large, rounded appearance of these lesions, often evident on chest radiographs or CT scans.
According to the World Health Organization, lung cancer was responsible for approximately 10 million deaths in 2020. [2] The most common cause of lung cancer is long-term exposure to tobacco smoke, and the carcinogens are typically found in cigarettes. [3] In the United States, around 80%-90% of lung cancer deaths are among cigarette smokers. [4]
Caplan syndrome is a nodular condition of the lung occurring in dust-exposed persons with either a history of rheumatoid arthritis (RA) or who subsequently develop RA within the following 5–10 years. [3] The nodules in the lung typically occur bilaterally and peripherally, on a background of simple coal workers' pneumoconiosis. There are ...
A lung nodule or pulmonary nodule is a relatively small focal density in the lung. A solitary pulmonary nodule (SPN) or coin lesion, [1] is a mass in the lung smaller than three centimeters in diameter. A pulmonary micronodule has a diameter of less than three millimetres. [2] There may also be multiple nodules. One or more lung nodules can be ...
[3] Early symptoms of ARS typically include nausea, vomiting, headaches, fatigue, fever, and a short period of skin reddening. [3] These symptoms may occur at radiation doses as low as 0.35 grays (35 rad). These symptoms are common to many illnesses, and may not, by themselves, indicate acute radiation sickness. [3]
It also includes lung manifestations of autoimmune diseases such as Sjögren syndrome or rheumatoid arthritis. [ 3 ] [ 4 ] Histopathologic studies have shown that the tree-in-bud pattern is caused by demarcation of the normally invisible branching course of the peripheral airways, which usually results from bronchioles being plugged or blocked ...
The occurrence of nodules in the lungs of miners exposed to silica dust was known as Caplan’s syndrome. [2] Rarely, the nodules occur at diverse sites on body (e.g., upper eyelid, distal region of the soles of the feet, vulva, and internally in the gallbladder, lung, heart valves, larynx, and spine). [3]
CT-guided biopsy of peripheral typical carcinoid tumor. The definitive diagnosis is rendered by a microscopic examination, after excision.Typical carcinoids have cells with stippled chromatin and a moderate quantity of cytoplasm.
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