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  2. Common thyroid drug levothyroxine linked to bone mass loss - AOL

    www.aol.com/common-thyroid-drug-levothyroxine...

    A recent abstract presented at the annual meeting of the Radiological Society of North America suggested that levothyroxine use in people with typical hormone ranges could lead to lower bone mass ...

  3. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [8]

  4. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    An increase in TSH above the normal range indicates under-replacement or poor compliance with therapy. A significant reduction in TSH suggests over-treatment. In both cases, a change in dose may be required. A low or low-normal TSH value may also signal pituitary disease in the absence of replacement. [citation needed]

  5. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    When pregnant, a woman with a low-functioning thyroid will also need to increase her dosage of thyroid hormone. [16] One exception is that thyroid hormones may aggravate heart conditions, especially in older patients; therefore, doctors may start these patients on a lower dose and work up to a larger one to avoid risk of heart attack. [17]

  6. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The TRH stimulates the anterior pituitary to produce thyroid-stimulating hormone (TSH). The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH ...

  7. Thyroid - Wikipedia

    en.wikipedia.org/wiki/Thyroid

    The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi). Microscopically, the functional unit of the thyroid gland is the spherical thyroid follicle , lined with follicular cells (thyrocytes), and occasional parafollicular cells that surround a lumen containing colloid .

  8. Levothyroxine - Wikipedia

    en.wikipedia.org/wiki/Levothyroxine

    For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should not be initiated at the full replacement dose. [24] Since thyroid hormone increases the heart's oxygen demand by increasing heart rate and contractility, starting at higher doses may cause an acute coronary syndrome or an ...

  9. Euthyroid sick syndrome - Wikipedia

    en.wikipedia.org/wiki/Euthyroid_sick_syndrome

    Fasting in healthy, euthyroid people causes reduced T3 and elevated rT3, although TSH is usually unchanged. [3] [5] [10] Even moderate weight loss can lower T3. [2] This may be primarily via reduced levels of leptin (the satisfaction hormone). Low leptin levels can downregulate hypothalamic TRH neurons and cause a reduction in TSH.

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