Search results
Results from the WOW.Com Content Network
Benzyl chloride also reacts readily with metallic magnesium to produce a Grignard reagent. [5] It is preferable over benzyl bromide for the preparation of this reagent, since the reaction of the bromide with magnesium tends to form the Wurtz coupling product 1,2-diphenylethane .
Benzyl group and derivatives: Benzyl group, benzyl radical, benzyl amine, benzyl bromide, benzyl chloroformate, and benzyl methyl ether. R = heteroatom, alkyl, aryl, allyl etc. or other substituents. In organic chemistry, benzyl is the substituent or molecular fragment possessing the structure R−CH 2 −C 6 H 5.
For example, benzyl chloroformate is used to introduce the Cbz (carboxybenzyl) protecting group and fluorenylmethyloxycarbonyl chloride is used to introduce the FMOC protecting group. Chloroformates are popular in the field of chromatography as derivatization agents.
Benzyl chloroformate, also known as benzyl chlorocarbonate or Z-chloride, is the benzyl ester of chloroformic acid. It can be also described as the chloride of the benzyloxycarbonyl (Cbz or Z) group. In its pure form it is a water-sensitive oily colorless liquid, although impure samples usually appear yellow.
Benzoyl chloride, also known as benzenecarbonyl chloride, is an organochlorine compound with the formula C 7 H 5 ClO. It is a colourless, fuming liquid with an irritating odour, and consists of a benzene ring ( C 6 H 6 ) with an acyl chloride ( −C(=O)Cl ) substituent .
The benzyl alcohol thus formed is quickly converted to the chloride under the reaction conditions. Mechanism of Blanc chloromethylation Other possibilities for the electrophile include (chloromethyl)oxonium cation (ClH 2 C–OH 2 + ) or chlorocarbenium cation (ClCH 2 + ), which may be formed in the presence of zinc chloride. [ 4 ]
Denatonium is a quaternary ammonium cation.It is composed as a salt with any of several anions, such as benzoate or saccharinate.It can be obtained by the quaternization of lidocaine, a popular anesthetic, with benzyl chloride or a similar reagent. [5]
4-Vinylbenzyl chloride is an organic compound with the formula ClCH 2 C 6 H 4 CH=CH 2. It is a bifunctional molecule, featuring both vinyl and a benzylic chloride functional groups . It is a colorless liquid that is typically stored with a stabilizer to suppress polymerization.