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Traditional serrated adenoma is a premalignant type of polyp found in the colon, often in the distal colon (sigmoid, rectum). Traditional serrated adenomas are a type of serrated polyp, and may occur sporadically or as a part of serrated polyposis syndrome. Traditional serrated adenomas are relatively rare, accounting for less than 1% of all ...
A sessile serrated adenoma or traditional serrated adenoma is suspected if there is either of the following: [4] Nuclear stratification; Loss of polarity; Dysplasia; A sessile serrated adenoma is suspected in case of any of the following: [4] Size ≥0.5 cm; Location in right colon; If both are present, it is almost always an SSA.
The serrated polyposis syndrome (SPS) is a relatively rare condition characterized by multiple and/or large serrated polyps of the colon. Serrated polyps include SSLs, hyperplastic polyps, and traditional serrated adenomas. Diagnosis of this disease is made by the fulfillment of any of the World Health Organization's (WHO) clinical criteria. [4]
Traditional serrated adenoma seen under microscopy with H&E stain, showing serrated crypts. SPS may occur with one of two phenotypes: distal or proximal. [6] The distal phenotype may demonstrate numerous small polyps in the distal colon and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). [6]
Tubular adenomas (tube-like shape) are the most common of the adenomatous polyps; they may occur everywhere in the colon and they are the least likely colon polyps to develop into colon cancer; Tubulovillous; Villous adenomas are commonly found in the rectal area and they are normally larger in size than the other two types of adenomas.
Colorectal adenoma Type Risk of containing malignant cells Histopathology definition Tubular adenoma 2% at 1.5 cm [4] Over 75% of volume has tubular appearance. [5] Tubulovillous adenoma 20% to 25% [6] 25–75% villous [5] Villous adenoma 15% [7] to 40% [6] Over 75% villous [5] Sessile serrated adenoma (SSA) [8] Basal dilation of the crypts ...
An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs , including the adrenal glands , pituitary gland , thyroid , prostate , and others.
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