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An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
Thiazide (/ ˈ θ aɪ ə z aɪ d /) refers to both a class of sulfur-containing organic molecules [1] and a class of diuretics based on the chemical structure of benzothiadiazine. [2] The thiazide drug class was discovered and developed at Merck and Co. in the 1950s. [ 3 ]
Meanwhile, according to 2013 European Society of Cardiology (ESC) guidelines, a loop diuretic can only replace thiazide-type diuretics if there is renal impairment (Creatinine of more than 1.5 mg/dL or estimated glomerular filtration rate (eGFR) of less 30 mL/min/1.73 m 2 due to lack of long term cardiovascular outcome data and appropriate ...
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Veterinary equivalency is the mutual recognition by two or more countries that each party's safety and sanitation standards for animal products, even where not identical, provide an equivalent level of protection to public and animal health. Aimed at facilitating trade, the practical effect of veterinary equivalency is that each country's ...
In the United States, meloxicam is approved for use only in canines, whereas (due to concerns about liver damage) it carries warnings against its use in cats [168] [169] except for one-time use during surgery. [170] In spite of these warnings, meloxicam is frequently prescribed "off-label" for non-canine animals including cats and livestock ...
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