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  2. Thalidomide - Wikipedia

    en.wikipedia.org/wiki/Thalidomide

    Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy such as skin lesions).

  3. Cereblon E3 ligase modulator - Wikipedia

    en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

    The problems with thalidomide included teratogenic side effects, high incidence of other adverse reactions, poor solubility in water and poor absorption from the intestines. In 1998 thalidomide was approved by the U.S. Food and Drug Administration (FDA) for use in newly diagnosed multiple myeloma (MM) under strict regulations. [2]

  4. List of thalidomide side effects - Wikipedia

    en.wikipedia.org/wiki/List_of_thalidomide_side...

    Adverse effects by frequency: [1] [2] Note that teratogenicity is not discussed here as it is not considered a side effect. For information regarding birth defects, see thalidomide .

  5. Chemotherapy-induced peripheral neuropathy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy-induced...

    The side effects of receiving bortezomib include chronic, distal, and symmetrical sensory peripheral neuropathy and neuropathic pain syndrome which may last for weeks, months, or years after treatment completion. [citation needed] 6) Immunomodulatory drugs, mainly thalidomide, are used to treat multiple myeloma. [3]

  6. DT-PACE - Wikipedia

    en.wikipedia.org/wiki/DT-PACE

    DT-PACE refers to a chemotherapy regimen for multiple myeloma consisting of Dexamethasone, Thalidomide, Cisplatin or Platinol, Adriamycin or doxorubicin, Cyclophosphamide, and Etoposide. [ 1 ] References

  7. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    A 2016 study concluded that stem cell transplant is the preferred treatment for multiple myeloma. [107] There are two types of stem cell transplants to treat multiple myeloma. [108] In autologous hematopoietic stem-cell transplantation (ASCT) – the patient's stem cells are collected from the patient's blood. The patient is given high-dose ...

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