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Phosphate-buffered saline (PBS) is a buffer solution (pH ~ 7.4) commonly used in biological research. It is a water-based salt solution containing disodium hydrogen phosphate , sodium chloride and, in some formulations, potassium chloride and potassium dihydrogen phosphate .
Occupational safety and health ... 1. Flash point: 110 °C (230 °F; 383 K) Safety data sheet ... Tris-buffered saline or phosphate buffered saline at dilutions of 0. ...
An example SDS, including guidance for handling a hazardous substance and information on its composition and properties. A safety data sheet (SDS), [1] material safety data sheet (MSDS), or product safety data sheet (PSDS) is a document that lists information relating to occupational safety and health for the use of various substances and products.
Tripotassium phosphate has few industrial applications, however it is commonly used as a base in laboratory-scale organic chemistry. Being insoluble in organic solvents, it is an easily removed proton acceptor in organic synthesis .
The process involves scission of a pyrophosphate bond, analogous to hydrolysis. SMFP can also be prepared by treating tetrasodium pyrophosphate or disodium phosphate with hydrogen fluoride. [2] In the laboratory, SMFP can be prepared by hydrolysis of difluorophosphate ions with dilute sodium hydroxide: PO 2 F 2 − + 2 NaOH → Na 2 PO 3 F + H ...
Buffer capacity falls to 33% of the maximum value at pH = pK a ± 1, to 10% at pH = pK a ± 1.5 and to 1% at pH = pK a ± 2. For this reason the most useful range is approximately p K a ± 1. When choosing a buffer for use at a specific pH, it should have a p K a value as close as possible to that pH.
McIlvaine buffer is a buffer solution composed of citric acid and disodium hydrogen phosphate, also known as citrate-phosphate buffer.It was introduced in 1921 by the United States agronomist Theodore Clinton McIlvaine (1875–1959) from West Virginia University, and it can be prepared in pH 2.2 to 8 by mixing two stock solutions.
The use of Phospho soda has been known to lead to acute phosphate nephropathy. According to the U.S. Food and Drug Administration (FDA), "Acute phosphate nephropathy is a form of acute kidney injury that is associated with deposits of calcium-phosphate crystals in the renal tubules that may result in permanent renal function impairment.