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Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
First, blood is drawn and a baseline TSH level is measured. Then, TRH is administered via a vein. After 30 minutes blood is drawn again and the levels of TSH are measured and compared to the baseline. Some authors recommend additional blood sampling at 15 minutes. In children, late blood sampling at 60 to 120 minutes is necessary.
Endocrinology is a branch of internal medicine dealing with hormones, the chemical messengers released internally to regulate the body's physiologic functions. [1] [2] Endocrinologists diagnose and manage diseases of endocrine glands, including hypothalamus, pituitary, thyroid, parathyroid, pancreatic islets, adrenals, testes, and ovaries.
Congenital iodine deficiency has been almost eliminated in developed countries through iodine supplementation of food and by newborn screening using a blood test for thyroid function. [5] Treatment consists of lifelong administration of thyroxine (T4). Thyroxine must be dosed as tablets only, even to newborns, as the liquid oral suspensions and ...
If dysfunction of the thyroid is suspected, laboratory tests can help support or rule out thyroid disease. Initial blood tests often include thyroid-stimulating hormone (TSH) and free thyroxine (T4). [9] Total and free triiodothyronine (T3) levels are less commonly used. [9] If autoimmune disease of the thyroid is suspected, blood tests looking ...
The first laboratory test to help assess thyroid status was the serum protein-bound iodine, which came into use around the 1950s. In 1971, the thyroid stimulating hormone (TSH) radioimmunoassay was developed, which was the most specific marker for assessing thyroid status in patients. [82]
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Most children born with congenital hypothyroidism and correctly treated with thyroxine grow and develop normally in all respects. Even most of those with athyreosis and undetectable T 4 levels at birth develop with normal intelligence, although as a population academic performance tends to be below that of siblings and mild learning problems ...
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