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Propofol administration also results in decreased cerebral blood flow, cerebral metabolic oxygen consumption, and intracranial pressure. [63] In addition, propofol may decrease intraocular pressure by as much as 50% in patients with normal intraocular pressure. [64] A more serious but rare side effect is dystonia. [65]
It takes 40 seconds for the effects of propofol to kick in, and effects last six minutes. [3] Propofol has both sedative and amnestic effects, but provides no analgesia. Adverse effects to look out for include hypotension (low blood pressure) and respiratory depression, manifested as mild drops in oxygen saturation levels.
Induced coma usually results in significant systemic adverse effects. The patient is likely to completely lose respiratory drive and require mechanical ventilation; gut motility is reduced; hypotension can complicate efforts to maintain cerebral perfusion pressure and often requires the use of vasopressor drugs. Hypokalemia often results.
To put this into perspective, some research shows that reducing your systolic blood pressure (top blood pressure reading) by 5 mmHg may lower your risk of cardiovascular events by 10%! The Bottom Line
"They have an impact in terms of blood pressure control and with that, can have significant beneficial impact on the cardiovascular system," AHA Volunteer President Dr. Keith Churchwell, who ...
81% achieve blood pressure control after one month. The scientists also discovered that after only one month, 81% of study participants receiving the GMRx2 combination pill achieved clinic ...
Close monitoring by the anesthesia provider will sometimes be provided, to help keep the patient comfortable during a medical procedure, along with other drugs to help relax the body. It can also help control breathing, blood pressure, blood flow, and heart rate and rhythm, when needed. [1] There are four levels of sedation by anesthesia.
Normal is near 120/80, and while the person's blood pressure still might not be normal, the procedure has reduced the blood pressure, putting less strain on the heart and other organs.
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