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Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [6]The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied; [7] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).
Adapalene Gel, sold in trade name Differin in China. Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6]
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
A hairdo like the Komondor’s comes with a considerable grooming burden. Their long, corded coats require regular grooming, and every so often the coat clumps up and needs time-consuming separation.
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This collar has a long-lasting formula that protects dogs and puppies from fleas and ticks for up to eight months. It starts working within 24 hours to offer fast relief to your pooch. View Deal
Anorexia, skin lesions, hair loss, hepatosplenomegaly, papilloedema, bleeding, general malaise, pseudotumor cerebri, and death may also occur. [26] Similar effects occur with other retinoids, except for 13-cis retinoic acid and its derivatives, such as adapalene.
Dogs are susceptible to allergies much like their human companions. Most allergies occur in dogs over 6 months old. A dog that is repeatedly exposed to a particular allergen becomes sensitized to it, and the immune system overreacts to a subsequent exposure, most commonly manifesting in the form of skin irritation. [1]
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