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The most common cause is androgenetic alopecia, also known as male pattern or female pattern hair loss due to the effects of dihydrotestosterone (DHT) on the hair follicles. A variety of factors may lead to this condition such as hormonal effects , age, diet, autoimmunity , emotional stress, physical stress, drug effects, genetics , or infections .
The EC 50 of DHT for activation of the AR is 0.13 nM, which is about 5-fold stronger than that of testosterone (EC 50 = 0.66 nM). [50] In bioassays, DHT has been found to be 2.5- to 10-fold more potent than testosterone. [47] The elimination half-life of DHT in the body (53 minutes) is longer than that of testosterone (34 minutes), and this may ...
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
However, when T levels are reduced through ADT, the body may compensate by increasing the production of P4, which can then serve as a substrate for the backdoor pathway. One of the main drawbacks of this increased production of P4 leads to an increase in DHT levels, which fuel the growth of prostate cancer cells.
Find out how age and weight go together, here. Plus, expert tips for losing weight after 50, including diet plans, calorie needs, and low-impact workouts.
Pattern hair loss (also known as androgenetic alopecia (AGA) [1]) is a hair loss condition that primarily affects the top and front of the scalp. [2] [3] In male-pattern hair loss (MPHL), the hair loss typically presents itself as either a receding front hairline, loss of hair on the crown and vertex of the scalp, or a combination of both.
The fitness pro previously demonstrated three simple moves for women over 50 (targeting the arms, back, and shoulders), a calorie-burning aerobic exercise, a #FitOver50 workout for lean legs, and ...
The “spacing effect” refers to a phenomenon whereby learning, or the creation of a memory, occurs more effectively when information, or exposure to a stimulus, is spaced out.
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