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Geschwind syndrome, also known as Gastaut–Geschwind syndrome, is a group of behavioral phenomena evident in some people with temporal lobe epilepsy.It is named for one of the first individuals to categorize the symptoms, Norman Geschwind, who published prolifically on the topic from 1973 to 1984. [1]
A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss.
The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. [3] The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. [4]: 21 Temporal refers to the head's temples.
It is a symptom associated with temporal lobe changes in epilepsy and in Geschwind syndrome. [1] Structures that may have an effect on hypergraphia when damaged due to temporal lobe epilepsy are the hippocampus and Wernicke's area. Aside from temporal lobe epilepsy, chemical causes may be responsible for inducing hypergraphia.
Brain MRI is the mainstay of initial investigation pointing to limbic lobe pathology revealing increased T2 signal involving one or both temporal lobes in most cases. [ 22 ] [ 14 ] Serial MRI in LE starts as an acute disease with uni- or bilateral swollen temporomesial structures that are hyperintense on fluid attenuation inversion recovery and ...
The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memories, language comprehension, and emotion association. [10]: 21 Within the temporal lobe is an area of the brain called the hippocampus which is associated with forming new memories and learning new things. The hippocampus ...
Klüver–Bucy syndrome is a syndrome resulting from lesions of the medial temporal lobe, particularly Brodmann area 38, [1] causing compulsive eating, hypersexuality, a compulsive need to insert inappropriate objects in the mouth (hyperorality), visual agnosia, and docility.
Hippocampus (Medial Temporal Lobe) Dentate gyrus; Cornu ammonis (CA fields) Cornu ammonis area 1 (CA1) Cornu ammonis area 2 (CA2) Cornu ammonis area 3 (CA3) Cornu ammonis area 4 (CA4) Amygdala (limbic system) (limbic lobe) Central nucleus (autonomic nervous system) Medial nucleus (accessory olfactory system) Cortical and basomedial nuclei (main ...