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  2. John Legend's Skincare Line Is Made for Melanin-Rich Skin - AOL

    www.aol.com/john-legends-skincare-line-made...

    To make this happen quickly, he partnered with A-Frame, a Los Angeles based brand incubator that's helped launch BIPOC celebrity-led brands including Kinlò, a skincare line from tennis sensation ...

  3. John Legend's Loved01 line for 'melanin-rich' skin hits ... - AOL

    www.aol.com/lifestyle/john-legends-loved01-line...

    John Legend's new affordable, unisex skin care line for "melanin-rich skin" is enjoying the spotlight and being slathered with high praise from beauty editors and shoppers alike.

  4. Nilotinib - Wikipedia

    en.wikipedia.org/wiki/Nilotinib

    Nilotinib is a Bcr-Abl tyrosine kinase inhibitor and works by interfering with signalling within the cancer cell. [3] [8] Nilotinib was approved for medical use in the United States in 2007. [3] [8] It is on the World Health Organization's List of Essential Medicines. [9] It is approved as a generic medication. [10]

  5. Tyrosine kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Tyrosine_kinase_inhibitor

    A tyrosine kinase inhibitor (TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activation of many proteins by signal transduction cascades. The proteins are activated by adding a phosphate group to the protein (phosphorylation), a step that TKIs inhibit. TKIs are typically used as ...

  6. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Tyrosine kinase inhibitor (TKI) with selective activity against RET, VEGFR-2 and EGFR: Medullary thyroid cancer. Diarrhoea, hypertension, QT interval prolongation, depression, electrolyte anomalies, hypothyroidism and GI perforation (uncommon). 2.3 mTOR inhibitors: Everolimus: PO: mTOR inhibitor.

  7. Gusacitinib - Wikipedia

    en.wikipedia.org/wiki/Gusacitinib

    Gusacitinib (ASN002) is an investigational drug which acts as a pan-Janus kinase inhibitor, binding with similar affinity at JAK1, JAK2, JAK3 and TYK2, and also inhibiting spleen tyrosine kinase (SYK). [1] It is taken orally and was developed for the treatment of eczema and dermatitis. [2] [3] [4]

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