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Tricyclics have a narrow therapeutic index, i.e., the therapeutic dose is close to the toxic dose. [7] Factors that increase the risk of toxicity include advancing age, cardiac status, and concomitant use of other drugs. [8] However, serum drug levels are not useful for evaluating risk of arrhythmia or seizure in tricyclic overdose. [9]
Cardiac arrest (also known as ... The second dose is given as a 600 mg bolus. [82] Additional medications. Bicarbonate, given as sodium bicarbonate, ...
Acidosis (hydrogen cation excess) is an abnormal pH in the body as a result of lactic acidosis which occurs in prolonged hypoxia and in severe infection, diabetic ketoacidosis, kidney failure causing uremia, or ingestion of toxic agents or overdose of pharmacological agents, such as aspirin and other salicylates, ethanol, ethylene glycol and other alcohols, tricyclic antidepressants, isoniazid ...
High mortality rates due to cardiac injury though, made surgeons to look on how to protect the heart. In 1955 D.G. Melrose suggested ‘’elective cardiac arrest’’, a technique already used for other purposes, in order to protect the heart from ischemia- since cardiac muscle is not working, oxygen demands should be low. In the 1960’s ...
A crash cart at the John D. Dingell VA Medical Center in Detroit, Michigan.. A crash cart, code cart, crash trolley or "MAX cart" is a set of trays/drawers/shelves on wheels used in hospitals for transportation and dispensing of emergency medication/equipment at site of medical/surgical emergency for life support protocols (ACLS/ALS) to potentially save someone's life.
Intraosseous access has roughly the same absorption rate as IV access, and allows for fluid resuscitation. For example, sodium bicarbonate can be administered IO during a cardiac arrest when IV access is unavailable. [1] High flow rates are attainable with an IO infusion, up to 125 milliliters per minute.
Potassium and sodium bicarbonate are excreted in the urine. This phase may last as long as 12 hours. [10] Phase II is characterized by paradoxic aciduria in the presence of continued respiratory alkalosis occurs when sufficient potassium has been lost from the kidneys. This phase may begin within hours and may last 12–24 hours. [10]
The LUCAS can be used both in and out of the hospital setting. [6] [7] The 2015 European Resuscitation Council Guidelines for Resuscitation does not recommend using mechanical chest compression on a routine basis, but are good alternative for situations where it may be difficult or to maintain continuous high-quality compressions, or when it may be too strenuous on the medic to do so. [8]