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The Golgi apparatus (/ ˈ ɡ ɒ l dʒ i /), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. [1] Part of the endomembrane system in the cytoplasm , it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination.
Receptors embedded in the membrane of the Golgi body bind specific cargo (such as dopamine) on the lumenal side of the vesicle. These cargo receptors then recruit a variety of proteins including other cargo receptors and coat proteins such as clathrin, COPI and COPII. As more and more of these coating proteins come together, they cause the ...
The Golgi apparatus (also known as the Golgi body and the Golgi complex) is composed of separate sacs called cisternae. Its shape is similar to a stack of pancakes. The number of these stacks varies with the specific function of the cell. The Golgi apparatus is used by the cell for further protein modification.
Golgi impregnations. Images of the brain of flies. Visualization of dendritic spines using Golgi Method. SynapseWeb. Includes a time-lapse study of Golgi impregnation. Berrebi, Albert: Cell Biology of Neurons: Structure and Methods of Study. (in PDF) Stained brain slice images which include the "Golgi-stained neurons" at the BrainMaps project
The cis-Golgi network is involved in the phosphorylation of oligosaccharides on lysosomal proteins, a modification that helps target proteins to the lysosomes. The medial-Golgi is the site of important reactions like the trimming of mannose and the addition of GlcNAc, which is essential for the formation of complex glycan structures.
In 1903, Nikolai K. Koltsov proposed that the shape of cells was determined by a network of tubules that he termed the cytoskeleton. The concept of a protein mosaic that dynamically coordinated cytoplasmic biochemistry was proposed by Rudolph Peters in 1929 [12] while the term (cytosquelette, in French) was first introduced by French embryologist Paul Wintrebert in 1931.
Golgi apparatus (also called the Golgi body, Golgi complex, or dictyosome), an organelle in a eukaryotic cell; Golgi tendon organ, a proprioceptive sensory receptor organ; Golgi's method or Golgi stain, a nervous tissue staining technique; Golgi alpha-mannosidase II, an enzyme; Golgi cell, a type of interneuron found in the cerebellum
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. [ 6 ]