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CPAF (Chlamydia Protease-like Activity Factor) functions by preventing the host from triggering the proper immune response. C. trachomatis use of CPAF targets and cleaves proteins that restructure the Golgi apparatus and activate DNA repair so that C. trachomatis is able to use the host cell machinery and proteins to its advantage. [26]
Molecular Koch's postulates are a set of experimental criteria that must be satisfied to show that a gene found in a pathogenic microorganism encodes a product that contributes to the disease caused by the pathogen.
Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium Chlamydia trachomatis. [3] Most people who are infected have no symptoms. [ 1 ] When symptoms do appear, they may occur only several weeks after infection; [ 1 ] the incubation period between exposure and being able to infect ...
Pathogenomics is a field which uses high-throughput screening technology and bioinformatics to study encoded microbe resistance, as well as virulence factors (VFs), which enable a microorganism to infect a host and possibly cause disease.
Chlamydia (sexually transmitted disease), Pseudomonas (infects humans, animals and plants) and the; Plant pathogens such as Erwinia, Ralstonia and Xanthomonas, and the plant symbiont Rhizobium. The T3SS is composed of approximately 30 different proteins, making it one of the most complex secretion systems.
Of various Chlamydiota that cause human disease, the two most important species are Chlamydia pneumoniae, which causes a type of pneumonia, and Chlamydia trachomatis, which causes chlamydia. Chlamydia is the most common bacterial sexually transmitted infection in the United States, and 2.86 million chlamydia infections are reported annually.
Chlamydia species produce a small amount of detectable glycogen and have two ribosomal operons. Chlamydia trachomatis is the cause of an infection commonly transmitted sexually (often referred as just "Chlamydia") and also is the cause of trachoma , an infectious eye disease, spread by eye, nose, and throat secretions.
The cytolytic peptide Candidalysin is produced during hyphal formation by Candida albicans; it is an example of a virulence factor from a fungus. Other virulence factors include factors required for biofilm formation (e.g. sortases) and integrins (e.g. beta-1 and 3). [7]
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