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Conivaptan, sold under the brand name Vaprisol, is a non-peptide inhibitor of the receptor for anti-diuretic hormone, also called vasopressin. It was approved in 2004 for hyponatremia (low blood sodium levels).
RG7713, or RG-7713, also known as RO5028442, is a small-molecule vasopression V 1A receptor antagonist which is or was under development for the treatment of pervasive developmental disorders or autism.
Tolvaptan and conivaptan antagonize the effects of antidiuretic hormone (vasopressin), thereby promoting the specific excretion of free water, directly ameliorating the volume overloaded state, and counteracting the hyponatremia that occurs due to the release of neuroendocrine hormones in an attempt to counteract the effects of heart failure.
Please review the contents of the section and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed . Find sources: "Vasopressin" medication – news · newspapers · books · scholar · JSTOR ( September 2018 )
We’re ready for a whole new set of explorations in 2025 with picks for 25 top places to visit. Take cues from the worst-behaved travelers of 2024 for what not to do in the year ahead.
In this creamy radish soup recipe, radishes are sautéed and pureed with potato, creating a velvety, healthy soup. Cooking radishes also tones down any bitterness while leaving plenty of sweet ...
Hypertension - A systematic review by the Cochrane Hypertension group assessing the anti-hypertensive effects of loop diuretics found only a modest reduction in blood pressure when compared to placebo. [14] According to Joint National Committee (JNC-8) guidelines, the first line treatment of hypertension is thiazide diuretics. The use of loop ...
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