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Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. [1] This includes respiratory tract infections , skin infections , chlamydia infections , pelvic inflammatory disease , and syphilis . [ 1 ]
Erythromycin/benzoyl peroxide is a prescription medication. [ 2 ] Side effects include dry skin, stinging, redness, and itchy rash ( urticaria ), [ 2 ] with recommended usage is 2 times per day, once in the morning and once in the evening, or as prescribed by a doctor.
Prolonged cardiac QT interval (especially erythromycin) Hearing loss (especially at higher doses) Jaundice; Inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, thereby inhibiting translocation of peptidyl tRNA. Clarithromycin: Biaxin: Erythromycin: Erythocin, Erythroped: Roxithromycin ...
Erythromycin.The macrolide ring is the lactone (cyclic ester) at upper left. Clarithromycin Roxithromycin. Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached.
Erythromycin is a bacteriostatic macrolide antibiotic used to treat bacterial infections, including the inhibition of bacteria linked with acne, such Cutibacterium acnes. The mechanism of action is poorly understood.
Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. [2] Cytochrome P450 eryF (CYP107A1) originally from the bacterium is responsible for the biosynthesis of the antibiotic by C6-hydroxylation of the macrolide 6-deoxyerythronolide B. [3] [4]
[45] [106] The overuse of antibiotics, like penicillin and erythromycin, has been associated with emerging antibiotic resistance since the 1950s. [86] [107] Widespread usage of antibiotics in hospitals has also been associated with increases in bacterial strains and species that no longer respond to treatment with the most common antibiotics. [107]
Discovery of erythromycin Abelardo Aguilar (November 3, 1917 – September 22, 1993 was a Filipino doctor from Iloilo , Philippines who worked as a medical representative for Eli Lilly and Company .