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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Any antiretroviral drug: Black tar heroin: Whoonga, Nyaope [8] Widespread use in South Africa. Whoonga is classically reputed to be a combination of heroin with antiretroviral drugs such as ritonavir and/or efavirenz, often combined with additional drugs such as cannabis or hashish, methamphetamine and/or methaqualone: Any deliriant or diphen ...

  3. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    The AUC (from zero to infinity) represents the total drug exposure across time. AUC is a useful metric when trying to determine whether two formulations of the same dose (for example a capsule and a tablet) result in equal amounts of tissue or plasma exposure. Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic ...

  4. Parachute (drugs) - Wikipedia

    en.wikipedia.org/wiki/Parachute_(drugs)

    Parachuting or bombing is a method of swallowing drugs by rolling or folding powdered or crushed drugs in a piece of edible paper to ingest while avoiding the unpleasant taste of the chemical. [1] It is sometimes called a "snow bomb", especially if using cocaine. This method is used among many pharmaceuticals that are commonly crushed for ...

  5. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  6. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    Sometimes the term safety ratio is used, particularly when referring to psychoactive drugs used for non-therapeutic purposes, e.g. recreational use. [10] In such cases, the effective dose is the amount and frequency that produces the desired effect, which can vary, and can be greater or less than the therapeutically effective dose.

  7. Drug accumulation ratio - Wikipedia

    en.wikipedia.org/wiki/Drug_accumulation_ratio

    In pharmacokinetics, the drug accumulation ratio (R ac) is the ratio of accumulation of a drug under steady state conditions (i.e., after repeated administration) as compared to a single dose. The higher the value, the more the drug accumulates in the body. An R ac of 1 means no accumulation.

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  9. Pharmaceutical formulation - Wikipedia

    en.wikipedia.org/wiki/Pharmaceutical_formulation

    Formulated drugs are stored in container closure systems for extended periods of time. These include blisters, bottles, vials, ampules, syringes, and cartridges. The containers can be made from a variety of materials including glass, plastic, and metal. The drug may be stored as a solid, liquid, or gas.