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  2. Cholinergic crisis - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_crisis

    Flaccid paralysis resulting from cholinergic crisis can be distinguished from myasthenia gravis by the use of the drug edrophonium (Tensilon), as it only worsens the paralysis caused by cholinergic crisis but strengthens the muscle response in the case of myasthenia gravis. (Edrophonium is a cholinesterase inhibitor, hence increases the ...

  3. Cholinesterase reactivator - Wikipedia

    en.wikipedia.org/wiki/Cholinesterase_reactivator

    They are used as antidote for treating organophosphate ... Cholinesterase reactivators are indicated for anticholinesterase toxicity and cholinergic crisis, ...

  4. Anticholinergic - Wikipedia

    en.wikipedia.org/wiki/Anticholinergic

    Reversible acetylcholinesterase inhibitor agents such as physostigmine can be used as an antidote in life-threatening cases. Wider use is discouraged due to the significant side effects related to cholinergic excess including seizures, muscle weakness, bradycardia, bronchoconstriction, lacrimation, salivation, bronchorrhea, vomiting, and diarrhea.

  5. Trihexyphenidyl - Wikipedia

    en.wikipedia.org/wiki/Trihexyphenidyl

    In organophosphate poisoning, trihexyphenidyl is a more effective antidote than atropine to counteract the cholinergic crisis, seizures, and neuropathology. [12] Equivocal preliminary results from small studies exist for other dyskinesias, Huntington's chorea, Spasmodic torticollis. [medical citation needed]

  6. Physostigmine - Wikipedia

    en.wikipedia.org/wiki/Physostigmine

    Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying.Because it enhances the transmission of acetylcholine signals in the brain and can cross the blood–brain barrier, physostigmine salicylate is used to treat anticholinergic poisoning (that is, poisoning by substances that interfere with the transmission of acetylcholine signaling, such ...

  7. Organophosphate poisoning - Wikipedia

    en.wikipedia.org/wiki/Organophosphate_poisoning

    For people affected by cholinergic syndrome, atropine sulfate combined with an oxime is used to combat the effects of the acute OP poisoning. Diazepam is sometimes also administered if convulsions or muscle fasciculations begin. [16] The intermediate syndrome (IMS) appears in the interval between the end of the cholinergic crisis and the onset ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    The high dropout rates have provoked neither an internal crisis nor a re-evaluation of programming. Stamper dismissed dropouts as “attrition by personal choice.” An addict’s failure is considered a result of not being ready for treatment, never an indication that there might be a problem with the treatment itself.

  9. Acetylcholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase_inhibitor

    Cholinergic crisis. Actions on the neuromuscular junction may result in prolonged muscle contraction. [21] The effects of neostigmine on postoperative nausea and vomiting are controversial and there is not a clear linkage in clinical practice, however, there is good evidence to support the reduction in risk when anticholinergic agents are ...