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  2. Cholinergic crisis - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_crisis

    As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of ACh, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning. Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils).

  3. Cholinesterase reactivator - Wikipedia

    en.wikipedia.org/wiki/Cholinesterase_reactivator

    In the treatment of organophosphate toxicity, cholinesterase reactivators such as Pralidoxime reactivate inhibited AChE at peripheral nicotinic receptors.Since AChE mediates effects on both nicotinic and muscarinic receptors, cholinesterase reactivators are co-administered with muscarinic antagonists, primarily atropine.

  4. Physostigmine - Wikipedia

    en.wikipedia.org/wiki/Physostigmine

    Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying.Because it enhances the transmission of acetylcholine signals in the brain and can cross the blood–brain barrier, physostigmine salicylate is used to treat anticholinergic poisoning (that is, poisoning by substances that interfere with the transmission of acetylcholine signaling, such ...

  5. Ivermectin Drug Interactions in Cancer Treatment for Dogs - AOL

    www.aol.com/ivermectin-drug-interactions-cancer...

    Spinosad: This flea treatment may cause ivermectin to become toxic. In a study, neurotoxic signs were found in dogs, so if she is using this medication, it can cause her to fall over and have ...

  6. What Are the Possible Treatments for Cancer on My Dog's Jaw?

    www.aol.com/possible-treatments-cancer-dogs-jaw...

    The dose of ivermectin used did not have toxic effects in mice. ... Related: Natural Cancer Alternative Treatments for Your Dog. Sources. Bergman PJ. Canine oral melanoma. Clin Tech Small Anim ...

  7. Acetylcholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase_inhibitor

    Many other types of drug treatments may require a titration or stepping up phase. This strategy is used to build tolerance to adverse events or to reach a desired clinical effect. [ 21 ] This also prevents accidental overdose and is therefore recommended when initiating treatment with drugs that are extremely potent and/or toxic (drugs with a ...

  8. Vet-Approved Home Treatment for Senior Dogs with Arthritis - AOL

    www.aol.com/vet-approved-home-treatment-senior...

    Vet-Approved Home Treatment for Senior Dogs with Arthritis. Dr. Mark dos Anjos. December 27, 2024 at 5:05 AM ... there is a risk of poisoning if it is sweetened with xylitol. Related: ...

  9. Pyridostigmine - Wikipedia

    en.wikipedia.org/wiki/Pyridostigmine

    Pyridostigmine is an acetylcholinesterase inhibitor in the cholinergic family of medications. [3] It works by blocking the action of acetylcholinesterase and therefore increases the levels of acetylcholine. [3] Pyridostigmine was patented in 1945 and came into medical use in 1955. [4] It is on the World Health Organization's List of Essential ...

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