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Hyaluronic acid has been FDA-approved to treat osteoarthritis of the knee via intra-articular injection. [24] A 2012 review showed that the quality of studies supporting this use was mostly poor, with a general absence of significant benefits, and that intra-articular injection of HA could possibly cause adverse effects. [25]
The first commercially sold sodium hyaluronate had been developed by Endre Alexander Balazs under the brand name of Healon, manufactured by Pharmacia AB in Sweden in 1980. In 1986, sodium hyaluronate was used as an intra-articular injection to treat osteoarthritis of the knee with the product Hyalart/Hyalgan by Fidia of Italy. [27]
A 2016 review found a trend towards benefit in 2016 for lateral epicondylitis. [11] A 2017 review found tentative evidence in Achilles tendinopathy. [12] In 2012, a systematic review studying various injection therapies found that prolotherapy and hyaluronic acid injection therapies were more effective than placebo when treating lateral ...
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Several studies published in the National Health Institute have illustrated this, including one 2021 study showing that over 99% of cervical cancer cases are caused by “persistent genital high ...
Gwen Stefani's career-defining hit "Don't Speak" impacted more than just her music career.. The former No Doubt frontwoman opened up to People on Monday about how she "wouldn't be here" without ...
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