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Many people with chronic obstructive pulmonary disease have a low partial pressure of oxygen in the blood and high partial pressure of carbon dioxide.Treatment with supplemental oxygen may improve their well-being; alternatively, in some this can lead to the adverse effect of elevating the carbon dioxide content in the blood (hypercapnia) to levels that may become toxic.
Oxygen therapy can exacerbate the effects of paraquat poisoning and should be withheld unless severe respiratory distress or respiratory arrest is present. Paraquat poisoning is rare, with about 200 deaths globally from 1958 to 1978. [28] Oxygen therapy is not recommended for people with pulmonary fibrosis or bleomycin-associated lung damage. [29]
Heated humidified high-flow therapy, often simply called high flow therapy, is a type of respiratory support that delivers a flow of medical gas to a patient of up to 60 liters per minute and 100% oxygen through a large bore or high flow nasal cannula. Primarily studied in neonates, it has also been found effective in some adults to treat ...
Portable oxygen concentrator used with bottle humidifier. POCs operate on the same principle as a home concentrator, pressure swing adsorption. [6] The basic set up of a POC is a miniaturized air compressor, a cylinder filled containing the sieve, a pressure equalizing reservoir and valves and tubes.
Lack of oxygen response may indicate other modalities such as heated humidified high-flow therapy, continuous positive airway pressure or (if severe) endotracheal intubation and mechanical ventilation. . [citation needed] Type 2 respiratory failure often requires non-invasive ventilation (NIV) unless medical therapy can improve the situation. [15]
The supportive therapies focus on maximizing pulmonary function and preserving activity tolerance through oxygen therapy, bronchodilators, inhaled beta-adrenergic agonists, and diuretics. [10] Because there is no effective treatment for restrictive lung disease, prevention is key. [10]
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Ventilation is the movement of gas during breathing, and perfusion is the process of pulmonary blood circulation, which delivers oxygen to body tissues. [2] Anatomically, the lung structure, alveolar organization , and alveolar capillaries contribute to the physiological mechanism of ventilation and perfusion. [ 1 ]
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