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Malignant pleural effusion is a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining the outside of the lung and the wall of the chest cavity. [1] Lung cancer and breast cancer account for about 50-65% of malignant pleural effusions.
A pleural effusion is accumulation of excessive fluid in the pleural space, the potential space that surrounds each lung.Under normal conditions, pleural fluid is secreted by the parietal pleural capillaries at a rate of 0.6 millilitre per kilogram weight per hour, and is cleared by lymphatic absorption leaving behind only 5–15 millilitres of fluid, which helps to maintain a functional ...
Mesothelioma that affects the pleura can cause these signs and symptoms: [15] Chest wall pain; Pleural effusion, or fluid surrounding the lung; Shortness of breath – which could be due to a collapsed lung or the pleural effusion; Fatigue or anemia; Wheezing, hoarseness, or a cough; Blood in the sputum (fluid) coughed up
On radiological studies, a pleural pseudotumor is visualized as a biconcave or lenticular lesion using conventional chest x-rays and CT scans. The lesion is most commonly located in the minor (horizontal) fissure of the lung. A pleural pseudotumor is also associated with the presence of dependent pleural effusions. [9]
[4] [5] Variability in categorising small-cell lung cancer as limited or extensive occurs with reference to the extent of pleural effusion and nodal stations involvement. [4] [8] In addition, patients with an ipsilateral pleural effusion are frequently excluded from the limited-disease category.
Asbestos-related diseases are disorders of the lung and pleura caused by the inhalation of asbestos fibres. Asbestos-related diseases include non-malignant disorders such as asbestosis (pulmonary fibrosis due to asbestos), diffuse pleural thickening, pleural plaques, pleural effusion, rounded atelectasis and malignancies such as lung cancer and malignant mesothelioma.
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