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The dermatome is the dorsal portion of the paraxial mesoderm somite which gives rise to the skin . In the human embryo, it arises in the third week of embryogenesis. [2] It is formed when a dermomyotome (the remaining part of the somite left when the sclerotome migrates), splits to form the dermatome and the myotome. [2]
[1] As the primitive streak continues to regress, somites form from the paraxial mesoderm by "budding off" rostrally as somitomeres, or whorls of paraxial mesoderm cells, compact and separate into discrete bodies. The periodic nature of these splitting events has led many to say to that somitogenesis occurs via a clock-wavefront model, in which ...
A dermatome is an area of skin that is mainly supplied by afferent nerve fibres from the dorsal root of any given spinal nerve. [ 1 ] [ 2 ] There are 8 cervical nerves (C1 being an exception with no dermatome), 12 thoracic nerves , 5 lumbar nerves and 5 sacral nerves .
Together, these pathways provide the initial specification of the paraxial mesoderm and maintain this identity. [1] This specification process has now been fully recapitulated in vitro with the formation of paraxial mesoderm progenitors from pluripotent stem cells , using a directed differentiation approach.
The notochord and the neural tube activate the protein SHH, which helps the somite to form its sclerotome. The cells of the sclerotome express the protein PAX1 that induces the cartilage and bone formation. The neural tube activates the protein WNT1 that expresses PAX 2 so the somite creates the myotome and dermatome.
The following other wikis use this file: Usage on bs.wikipedia.org Dermatom; Miotom; Usage on en.wikiversity.org WikiJournal of Medicine/Medical gallery of Mikael Häggström 2014
In other words, there is no Power Four. There’s only a Power Two, and everyone else is left clawing at the scraps. The committee’s decision to rank Alabama No. 11 is telling.
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