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The first occurrence of the term "evolutionary mismatch" may have been in a paper by Jack E. Riggs published in the Journal of Clinical Epidemiology in 1993. [7] In the years to follow, the term evolutionary mismatch has become widely used to describe biological maladaptations in a wide range of disciplines.
The MMN is a response to a deviant within a sequence of otherwise regular stimuli; thus, in an experimental setting, it is produced when stimuli are presented in a many-to-one ratio; for example, in a sequence of sounds s s s s s s s d s s s s d s s s..., the d is the deviant or oddball stimulus, and will elicit an MMN response.
Matching is a statistical technique that evaluates the effect of a treatment by comparing the treated and the non-treated units in an observational study or quasi-experiment (i.e. when the treatment is not randomly assigned).
(For a factor A with two levels, scaled so that low = -1 and high = +1, the effect of A has a mean-unbiased estimator that is evaluated by subtracting the average observed response when A is -1 from the average observed response when A = +1 and dividing the result by 2; division by 2 is needed because the -1 level is 2 scaled units away from ...
Mismatch repair is a highly conserved process from prokaryotes to eukaryotes.The first evidence for mismatch repair was obtained from S. pneumoniae (the hexA and hexB genes).
It is violation of scientific integrity: violation of the scientific method and of research ethics in science, including in the design, conduct, and reporting of research. A Lancet review on Handling of Scientific Misconduct in Scandinavian countries provides the following sample definitions, [1] reproduced in The COPE report 1999: [2]
Scientific terminology is the part of the language that is used by scientists in the context of their professional activities. While studying nature, scientists often encounter or create new material or immaterial objects and concepts and are compelled to name them.
Research integrity or scientific integrity became an autonomous concept within scientific ethics in the late 1970s. In contrast with other forms of ethical misconducts, the debate over research integrity is focused on "victimless offence" that only hurts "the robustness of scientific record and public trust in science". [3]