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Neonatal sepsis of the newborn is an infection that has spread through the entire body. The inflammatory response to this systematic infection can be as serious as the infection itself. [26] In infants that weigh under 1500 g, sepsis is the most common cause of death. Three to four percent of infants per 1000 births contract sepsis.
Bronze baby syndrome (dark pigmentation of skin). The primary symptom is yellowish discoloration of the white part of the eyes and skin in a newborn baby. [1] Other symptoms may include excess sleepiness or poor feeding. [1] A bilirubin level more than 34 μmol/L (2 mg/dL) may be visible. [1]
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".
Newborns are especially vulnerable to this damage, due to increased permeability of the blood–brain barrier occurring with increased unconjugated bilirubin, simultaneous to the breakdown of fetal hemoglobin and the immaturity of gut flora. This condition has been rising in recent years, as babies spend less time in sunlight. [citation needed]
Intrapartum (during childbirth) fever (>38 °C, >100.4 °F) Amniotic infections (chorioamnionitis) Young maternal age; Maternal HIV infection [28] Nevertheless, most babies who develop GBS-EOD are born to colonized mothers without any of these risk factors. [12] Heavy GBS vaginal colonization may be associated with a higher risk for GBS-EOD.
Neonatal meningitis is a serious medical condition in infants that is rapidly fatal if untreated.Meningitis, an inflammation of the meninges, the protective membranes of the central nervous system, is more common in the neonatal period (infants less than 44 days old) than any other time in life, and is an important cause of morbidity and mortality globally.
Symptoms of a vertically transmitted infection may include fever and flu-like symptoms. The newborn is often small for gestational age. A petechial rash on the skin may be present, with small reddish or purplish spots due to bleeding from capillaries under the skin. An enlarged liver and spleen (hepatosplenomegaly) is common, as is jaundice ...
Postpartum infections, also known as childbed fever and puerperal fever, are any bacterial infections of the female reproductive tract following childbirth or miscarriage. [1] Signs and symptoms usually include a fever greater than 38.0 °C (100.4 °F), chills, lower abdominal pain, and possibly bad-smelling vaginal discharge . [ 1 ]
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