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The sodium oxybate component of Xywav was granted orphan drug designation in November 1994 by the FDA. [8] [6] Xywav is a prescription drug and a Schedule III controlled substance in the United States. [2]
An orphan drug is a pharmaceutical agent that is developed to treat certain rare medical conditions. An orphan drug would not be profitable to produce without government assistance, due to the small population of patients affected by the conditions. The conditions that orphan drugs are used to treat are referred to as orphan diseases. The ...
Historically, orphan drugs cost more than other drugs and have received special treatment since the enactment of the US Orphan Drug Act of 1983. However, these steep price increases of orphan and other specialty drugs has come under scrutiny. [13] The average cost of a specialty drug in the US was $65,000 annually in June 2013 (about $5,416 a ...
Orphan drugs -- medications meant for small patient populations with rare, dangerous diseases -- can be a rewarding business for biotech firms that strike gold. Drugs can cost hundreds of ...
Pentylenetetrazol has been used experimentally to study seizure phenomena and to identify pharmaceuticals that may control seizure susceptibility. For instance, researchers can induce status epilepticus in animal models. Pentylenetetrazol is also a prototypical anxiogenic drug and has been extensively used in animal models of anxiety.
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