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  2. Animal disease model - Wikipedia

    en.wikipedia.org/wiki/Animal_disease_model

    Humans share about 99% of our genome with chimpanzees [7] [8] (98.7% with bonobos) [9] and over 90% with the mouse. [6] With so much of the genome conserved across species, it is relatively impressive that the differences between humans and mice can be accounted for in approximately six thousand genes (of ~30,000 total). Scientists have been ...

  3. Comparative genomics - Wikipedia

    en.wikipedia.org/wiki/Comparative_genomics

    Similarity of related genomes is the basis of comparative genomics. If two creatures have a recent common ancestor, the differences between the two species genomes are evolved from the ancestors' genome. The closer the relationship between two organisms, the higher the similarities between their genomes.

  4. Evidence of common descent - Wikipedia

    en.wikipedia.org/wiki/Evidence_of_common_descent

    [10] [11] Genetic sequence evidence thus allows inference and quantification of genetic relatedness between humans and other apes. [ 12 ] [ 13 ] The sequence of the 16S ribosomal RNA gene, a vital gene encoding a part of the ribosome , was used to find the broad phylogenetic relationships between all extant life.

  5. Human evolutionary genetics - Wikipedia

    en.wikipedia.org/wiki/Human_evolutionary_genetics

    Human accelerated regions are areas of the genome that differ between humans and chimpanzees to a greater extent than can be explained by genetic drift over the time since the two species shared a common ancestor. These regions show signs of being subject to natural selection, leading to the evolution of distinctly human traits.

  6. Model organism - Wikipedia

    en.wikipedia.org/wiki/Model_organism

    Genomic data is used to make close comparisons between species and determine relatedness. Humans share about 99% of their genome with chimpanzees [61] [62] (98.7% with bonobos) [63] and over 90% with the mouse. [60] With so much of the genome conserved across species, it is relatively impressive that the differences between humans and mice can ...

  7. Sequence homology - Wikipedia

    en.wikipedia.org/wiki/Sequence_homology

    Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog. Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.

  8. Humanized mouse - Wikipedia

    en.wikipedia.org/wiki/Humanized_mouse

    A mouse-human hybrid is a genetically modified mouse whose genome has both mouse and human genes, thus being a murine form of a human-animal hybrid. For example, genetically modified mice may be born with human leukocyte antigen genes in order to provide a more realistic environment when introducing human white blood cells into them in order to ...

  9. The Ancestor's Tale - Wikipedia

    en.wikipedia.org/wiki/The_Ancestor's_Tale

    The Mouse's Tale talks about the close similarity between humans and mice and that we both share about 20,000 genes. The phenotypic difference comes from the study of epigenetics which is the expression of the DNA. The genome is not a blueprint where the more complex the animal, the more complex the blueprint ought to be.