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The mouse HoxA cluster shown here has 11 paralogous genes (2 are missing). [39] Paralogous genes can shape the structure of whole genomes and thus explain genome evolution to a large extent. Examples include the Homeobox genes in animals. These genes not only underwent gene duplications within chromosomes but also whole genome duplications. As ...
Global Alignments with Human C6ORF47 protein with the seven-gill sharpnose shark C6ORF47 protein showed two noticeable large gaps found from human C6ORF47 protein in amino acids 44-62 and 153-173 . These gaps were present in all descendants of vertebrates until rodents and rabbits.
In biology, homology is similarity in anatomical structures or genes between organisms of different taxa due to shared ancestry, regardless of current functional differences. Evolutionary biology explains homologous structures as retained heredity from a common ancestor after having been subjected to adaptive modifications for different ...
Comparative Maps NIH's National Library of Medicine NCBI link to Gene Homology resources, and Comparative Chromosome Maps of the Human, Mouse, and Rat. Graham Moore group research page - cereal genomics More information on synteny and its use in comparative cereal genomics.
228536 Ensembl ENSG00000140320 ENSMUSG00000040007 UniProt Q8TBE0 Q497V6 RefSeq (mRNA) NM_001301132 NM_014952 NM_001045523 RefSeq (protein) NP_001288061 NP_055767 n/a Location (UCSC) Chr 15: 40.44 – 40.47 Mb Chr 2: 118.73 – 118.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bromo adjacent homology domain containing 1 (BAHD1) is a protein that in humans is encoded by the BAHD1 ...
A mouse-human hybrid is a genetically modified mouse whose genome has both mouse and human genes, thus being a murine form of a human-animal hybrid. For example, genetically modified mice may be born with human leukocyte antigen genes in order to provide a more realistic environment when introducing human white blood cells into them in order to ...
There are four validated isoform variants of human GRAMD1B. [5] These consist of truncated 5’ and 3’ regions, resulting in the loss of an exon. One prominent analysis of the mouse gene predicts one form of Gramd1b that is 699 amino acids long. [8]
This is an indispensable tool for any researcher using the mouse as a model organism for their research, and for researchers interested in genes that share homology with the mouse genes. Various mouse research support resources including animal collections and free colony management software are also available at the MGI site. [7]