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Signs of folate deficiency anemia most of the time are subtle. [4] Anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency in adults. [1] Folate deficiency anemia may result in feeling tired, weakness, changes to the color of the skin or hair, open sores on the mouth, shortness of breath, palpitations, lightheadedness, cold hands and feet, headaches, easy bleeding ...
Research suggests that levomefolic acid (L-methylfolate) taken with a first-line antidepressant [6] provides a modest adjunctive antidepressant effect for individuals who do not respond or have only a partial therapeutic response to SSRI or SNRI medication, [7] [8] and might be a more cost-effective adjunctive agent than second-generation antipsychotics.
However, methotrexate can be toxic, [56] [57] [58] producing side effects such as inflammation in the digestive tract that make eating normally more difficult. Bone marrow depression (inducing leukopenia and thrombocytopenia) and acute kidney and liver failure have been reported.
There also are resveratrol supplements, the Mayo Clinic noted. "However, they might cause side effects," according to the Mayo Clinic. "And research suggests that the body can't absorb most of the ...
21% of Americans have chronic pain. A new study found that diets rich in vegetables, fruits, grains, lean proteins, and dairy was linked to less chronic pain.
The majority of menopausal women are deficient. Experts weigh in on the benefits of taking a vitamin D supplement in menopause.
Cerefolin is a prescription medication made by Pamlab that contains 5.635 mg of folate as L-methylfolate, 1 mg of vitamin B 12 as methylcobalamin, 50 mg of vitamin B 2 as riboflavin, and 5 mg of vitamin B 6 as pyridoxine. It is approved by the U.S. Food and Drug Administration for the treatment or prevention of vitamin deficiencies. [1]
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