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SARS‑CoV‑2 is a strain of the species Betacoronavirus pandemicum (SARSr-CoV), as is SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak. [ 2 ] [ 17 ] There are animal-borne coronavirus strains more closely related to SARS-CoV-2, the most closely known relative being the BANAL-52 bat coronavirus.
SARS-CoV-2 antigens can be detected before onset of COVID-19 symptoms (as soon as SARS-CoV-2 virus particles) with more rapid test results, but with less sensitivity than PCR tests for the virus. [57] COVID-19 rapid antigen tests are lateral flow immunoassays that detect the presence of a specific viral antigen, which indicates current viral ...
The most closely related bat coronavirus and SARS-CoV diverged in 1986. [81] The ancestors of SARS-CoV first infected leaf-nose bats of the genus Hipposideridae; subsequently, they spread to horseshoe bats in the species Rhinolophidae, then to Asian palm civets, and finally to humans. [82] [83]
The SARS-CoV-2 Kappa variant is also known as lineage B.1.617.1 and was first detected in India in December 2020. [191] By the end of March 2021, the Kappa sub-variant accounted for more than half of the sequences being submitted from India. [ 192 ]
Cases of the Alpha variant (lineage B.1.1.7) were estimated to be under-reported by most countries as the most commonly used tests do not distinguish between this variant and other SARS-CoV-2 variants, and as many SARS-CoV-2 infections are not detected at all. RNA sequencing is required for detection of this variant, [82] although RT-PCR test ...
COVID-19 rapid antigen tests or RATs, also frequently called COVID-19 lateral flow tests or LFTs, are rapid antigen tests used to detect SARS-CoV-2 infection ().They are quick to implement with minimal training, cost a fraction of other forms of COVID-19 testing, and give users a result within 5–30 minutes.
While SARS-CoV-2 RNA has been detected in the urine and feces of some persons infected with COVID-19, [a] there is no evidence of COVID-19 transmission through feces or urine. [ 19 ] [ 82 ] COVID-19 is not an insect-borne disease ; there is also no evidence that mosquito are a vector for COVID-19. [ 84 ]
A trace-back analysis of SARS negative nasopharyngeal aspirates from patients with respiratory illness during the SARS period in 2003, identified the presence of CoV-HKU1 RNA in the sample from a 35-year-old woman with pneumonia. [6]
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