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SARS‑CoV‑2 is a strain of the species Betacoronavirus pandemicum (SARSr-CoV), as is SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak. [ 2 ] [ 17 ] There are animal-borne coronavirus strains more closely related to SARS-CoV-2, the most closely known relative being the BANAL-52 bat coronavirus.
Some SARS-CoV-2 variants are considered to be of concern as they maintain (or even increase) their replication fitness in the face of rising population immunity, [14] either by infection recovery or via vaccination. Some of the variants of concern show mutations in the RBD of the S-protein. [15]
Delta (B.617.2) First identified in India in late 2020, the delta variant soon spread across the globe. It became the dominant variant of SARS-CoV-2 until the emergence of omicron in December 2021.
Severe acute respiratory syndrome coronavirus (SARS-CoV), β-CoV (identified in 2003) Middle East respiratory syndrome-related coronavirus (MERS-CoV), β-CoV (identified in 2012) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), β-CoV (identified in 2019) These cause the diseases commonly called SARS, MERS, and COVID-19 respectively.
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2.The disease spread worldwide, resulting in the COVID-19 pandemic.. The symptoms of COVID‑19 can vary but often include fever, [7] fatigue, cough, breathing difficulties, loss of smell, and loss of taste.
On 26 November 2021, the WHO's Technical Advisory Group on SARS-CoV-2 Virus Evolution declared PANGO lineage B.1.1.529 a variant of concern and designated it with the Greek letter omicron. [10] The WHO skipped the preceding letters nu and xi in the Greek alphabet to avoid confusion with the similarities of the English word "new" and the Chinese ...
A COVID-19 vaccine is intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 . Prior to the COVID-19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute ...
The binding potential of SARS-CoV-2 to pangolin ACE2 however is very low. [37] The receptor binding domain of SARS-CoV-2 has been hypothesized to originate from recombination of the relevant portion of pangolin-CoV with an RaTG13-like virus. [75] Deer mice are highly susceptible to SARS-CoV-2, making them potential reservoir or intermediate ...
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